The exact cause of keratoacanthoma is unknown, but long‑term sun exposure, ionizing radiation, chronic skin injury, and contact with certain chemicals seem to increase the risk. It is an acquired tumor, not something you are born with, and usually appears later in adult life.
Keratoacanthoma is considered an optional precancerous condition: most stay benign, but some can transform into squamous cell carcinoma, especially if chronically irritated or burned. People with keratoacanthoma also have a higher chance of developing other skin cancers nearby or elsewhere on the skin.
The main treatment for keratoacanthoma is surgical excision with a small margin of healthy skin, which both removes the tumor and allows precise histological examination. Simple shaving, superficial removal, or destructive methods like laser or cryotherapy alone are not ideal because they increase the risk of recurrence and can miss an underlying skin cancer.