Yintoni i-Pustular Psoriasis?
I-pustular psoriasis yindlela engavamiyanga kodwa ebalulekileyo ye-psoriasis ebonakaliswa nge-pustules ezingenabungozi (ezingasongelwa) kwi-epidermis ebonakalayo, ebomvu. Ngokungafani ne-plaque psoriasis eqhelekileyo, i-blisters ezimhlophe okanye eziphuzi ziqala phambili — ezi azinabakteriya. Le meko ihlukaniswe ngohlobo olukhawulezileyo (izandla, iinyawo) kunye neendlela ezijolise kumzimba wonke. Uhlobo olujolise kumzimba wonke lungaba yingozi empilweni kwaye ludinga ukunyanga ngokukhawuleza.
Iindlela ze-Pustular Psoriasis
Iindlela eziphambili ziyi: I-pustular psoriasis ejolise kumzimba wonke (GPP, uhlobo lwe-von Zumbusch) — ukuvela ngokukhawuleza kunye nefeva, i-erythema ebanzi, kunye nokwakhiwa kwe-pustule kumzimba, okungaba yingozi empilweni. I-palmoplantar pustulosis (uhlobo lwe-Barber) — i-pustules ezingenabungozi ezichaphazela iipalms kunye neepads zeenyawo ezithintela kakhulu ubomi bemihla ngemihla. I-acrodermatitis continua ye-Hallopeau — ukuvela kwe-pustule okuqhubekayo kwiingcambu zeengcambu kunye neenyawo okungaholela ekulahlekelweni kweenail kunye nezinguquko kumathambo.
Izizathu kunye neMikhwa
I-pustular psoriasis ibangelwa kukuphindaphinda okugqithisileyo kwesistim ye-immune, okuholela kumjikelo omkhulu we-neutrophil kwi-epidermis. Iimikhwa ezivamile ziquka: ukuvalwa ngokukhawuleza kwe-corticosteroids ezisebenzayo, iintsholongwane (ikakhulu i-streptococcal), ukukhulelwa (impetigo herpetiformis), uxinzelelo olukhulu lweemotions, ezinye iimeko, kunye nokutshaya. Iinguqulelo zejini kwi-gene ye-IL36RN ziye zafunyanwa kwiindlela zomndeni ze-GPP.
Iimpawu kunye neMiphumo
Kwi-form ejolise kumzimba wonke, ubomvu obubanzi be-epidermis obunezinkulungwane ze-pustules ezincinci bavele ngokuqinisekileyo, kuhlangene nefeva, i-chills, i-tachycardia, kunye nokungaphili kakuhle. I-pustules zingahlanganiswa zibe ziilwandle ze-pus. Iimpembelelo ziquka ukulahleka kwamanzi kunye ne-electrolyte, i-sepsis, kunye nokungaphumeleli kwee-organ.!! Kwi-form ye-palmoplantar, i-pustules ezibuhlungu kunye nokuphuma kwe-epidermis ezandleni naseenyaweni zibalulekile — rhoqo zineziphumo ezibalulekileyo kumsebenzi.
Uphando
Uphando lusekelwe kumfanekiso wezokwelapha kunye ne-biopsy yesikhumba, ebonisa ukwakheka kwepustule engaphantsi kwesikhumba kunye nokungena kwe-neutrophil — ngaphandle kokufumanisa i-pathogen (i-pustules ezihlambulukileyo). Ukuhlolwa kwelebhu ngokwesiqhelo kubonisa uphuhliso lweemakha zokuvuvukala (CRP, ESR), i-leukocytosis, kunye nokuba yi-hypoalbuminemia. Ukwehlukanisa kwi-pustuloses ezibangelwa yiintsholongwane kunye nezinye i-dermatoses ze-neutrophilic kubalulekile.
Ukwelashwa kunye noLawulo
Ukwelashwa kuxhomekeke kumgangatho kunye nobunzima. I-GPP ngokwesiqhelo ifuna ukungena esibhedlele kunye nemithi ye-systemic: i-cyclosporine yokulawula ngokukhawuleza, i-methotrexate, i-acitretin, okanye i-biologics (i-infliximab, i-spesolimab — i-antagonist ethile ye-IL-36 receptor). Kwi-form ye-palmoplantar, i-steroids ezinamandla, i-PUVA therapy, i-acitretin, kunye ne-biologics zihlala zikhona. Ukugwema i-trigger ezaziwayo kubalulekile, ngakumbi ukunciphisa kancinci i-steroids ze-systemic kunokuba kuvalwe ngokuqhuba.!!
Indlela i-AI Skin Analysis Enga Nceda Ngayo
I-pustular psoriasis — ngakumbi i-form ye-palmoplantar — ifuna ukugadwa ngokucophelela ukuze kulandelwe ubunzima bokuphuma kunye nempendulo yokwelashwa. I-Skinscanner ikuvumela ukuba uthathe umfanekiso wezandla zakho, iinyawo, okanye ezinye iindawo ezichaphazelekayo rhoqo, ukudala irekhodi elibonakalayo eliqinisekisa ubunzima be-pustule, ubomvu, kunye nokuphuma ngokuhamba kwexesha. Le ndawo ibalulekile kwiimeko zokwelashwa, ikunceda udokotela wakho ukuba aqonde ukuba ingaba umphumo wakho wexesha elikhoyo ulawula le ngxaki okanye ukuba zifunwa na utshintsho.
Kubaguli abaziwayo be-psoriasis, le app inganceda ukufumanisa iimpawu zokuqala ze-pustular flare — i-pustules ezintsha ezivela kwisikhumba esiqinileyo ngaphambili — ivumela ukungenelela kwangexesha. I-Skinscanner ayifuni ukufaka esikhundleni sokuvavanywa ngochwepheshe, okubalulekile kule ngxaki enokubangela ingozi, kodwa ixhasa ukugadwa ngokuzimeleyo kunye neengxoxo ze-clinical ezisebenzayo.
