Yintoni iLichen Planus?
ILichen planus yimeko yokuvuvukala engapheliyo enokuthi ithinte isikhumba, imithambo yokuphefumla, iinwele, kunye neenwele. Ibonakaliswa ngama-papules aphezulu, aphakathi kwepolygonal, anombala ophuzi-omnyama (purple-red) kunye nemigca emhlophe efana nenethi (Wickham's striae) ebusweni. Le meko ibangelwa yi-immune, ayiyingozi, kwaye ithinta malunga ne-1-2% yabantu — ikakhulu abantu abadala phakathi kweminyaka engama-30 kunye ne-60. Ithinta bobabini ubulili ngokulinganayo, nangona i-oral lichen planus ingase ibonakale ngaphezulu kwiingcuka.
Izizathu kunye nePathogenesis
ILichen planus yimpembelelo ye-autoimmune ebangelwa yi-T-cell ethintela umjikelo wesikhumba. Izikhumbuzo ezichanekileyo aziqondwa ngokupheleleyo. Kukho ubudlelwane ne-hepatitis C, ezinye iimeko (beta-blockers, ACE inhibitors, NSAIDs), iifilitha ze-dental amalgam, kunye ne-allergens zokuthintela.
Uxinzelelo lungaphucula ukutshisa. Kukho umphakathi wejenerikhi, njengoko le meko ihlala ibonakala kwiimuli. Iimpembelelo ezibangelwa ziimveliso zonyango zingafana ne-idiopathic lichen planus kwaye kufuneka ziqwalaselwe kwi-differential.
Iimpawu kunye neFom
I-5 Ps ezidumileyo zichaza iimeko zesikhumba: pruritic (ukuthintela), polygonal, planar (ephezulu), purple, kunye neepapules. Iindawo ezikhethiweyo ziquka iiwrist, iiforearms, iankles, kunye ne-back engaphantsi. I-oral lichen planus ibonakala njengeemigca ezimhlophe (reticular pattern), ukonakaliswa, okanye i-ulcerations kwi-buccal mucosa, ulwimi, okanye i-gums.
Ukuthintelwa kweenwele kungabandakanya ukunyuka, ukuncipha, okanye ukulahleka kweenwele ngokupheleleyo. Ipheno yeKoebner — ukuveliswa kweemeko ezintsha kwiindawo zokuphazamiseka — iyenzeka rhoqo kwaye ingachaza ukusasazeka kumamark scratch okanye kumaleko ebhanti.
Uphando
Uphando lusekelwe kumphumo wezokwelapha — i-Wickham's striae eqhelekileyo phantsi kwe-dermatoscopy ivame ukuba yinkcukacha. I-biopsy yesikhumba iqinisekisa uphando, ibonisa i-band-like lymphocytic infiltrate kwi-junction zone enokubangela umonakalo kwi-basal keratinocytes (interface dermatitis). Ukuze kuqinisekiswe i-oral lichen planus, i-biopsy ibaluleke kakhulu ukuze kuhlolwe utshintsho olungaphambi kokuba lube yingozi. Uhlolo lweHepatitis C lukhuthazwa, njengoko ubudlelwane bukhona kwiimfundo ezininzi.!!
Iindlela Zonyango
Iikhoritosteroids eziphathekayo ziyi ndlela yokuqala yokunyanga i-cutaneous lichen planus. Iikhoritosteroids ezinamandla ezifana ne-clobetasol propionate zisetshenziswa kwiimeko zesikhumba, ngelixa iifom ezithambileyo zilungile kwiimithambo yokuphefumla. I-calcinurin inhibitors (tacrolimus, pimecrolimus) zinika indlela engasetyenziswa i-steroid, ikakhulu kwiifom ze-oral kunye ne-genital.
Ukuze kuthathelwe ingqalelo ubukhulu, iindlela eziphathekayo zingaqwalaselwa: iikhoritosteroids eziphathwayo, i-retinoids (acitretin), i-methotrexate, okanye i-phototherapy (UVB, PUVA). I-antihistamines zinciphisa ukungakhululeki.
Uhlanga kunye nePrognosis
I-cutaneous lichen planus ikakhulu iyazikhusela, iphumeza kwiimeko ezininzi kwiimfuno phakathi kweenyanga ezi-1–2, nangona ingashiya i-post-inflammatory hyperpigmentation. I-Oral lichen planus ihlala ilandela umjikelo ohlala ixesha elide ofuna ukuphathwa ixesha elide — kuba iifom ezonakalisayo zineengozi ezincinci zokuguqulwa kokungafani kwi-squamous cell carcinoma, ukulawulwa rhoqo kubalulekile.!! Utshintsho kwiintsimbi lungahlala. Ukuphinda kubonakale kuyenzeka, kodwa i-prognosis jikelele ilungile.
Indlela i-AI Skin Analysis Ezingakunceda Ngayo
Iipapules ezahlukeneyo eziphuzi, ezinephezulu eflethi ye-lichen planus zingaxhaphakile ukudideka nezinye iimeko zokuvuvukala ezifana ne-psoriasis, ukuvela kwemithi, okanye i-eczema. I-Skinscanner ihlola umbala, umfanekiso, kunye nokusetyenziswa kweemeko zakho zesikhumba ukuze ikuncede uqonde ukuba iimpawu zakho zihambelana ne-lichen planus. Ukudokhumenti rhoqo ngeefoto kukuvumela ukuba ulandele umjikelo wezikhumbuzo ezikhoyo, ufumane ezitsha kwangoko, kwaye ulandele impendulo yakho kumphumo kwiiveki kunye neenyanga.
Le timeline yokubona ibalulekile kakhulu ekuphatheni iimeko ezingenakubalwa. Kubantu abane-post-inflammatory hyperpigmentation emva kokuba i-lichen planus iphelile, i-Skinscanner ingakunceda ulandele ukuncipha kancinci. I-Skinscanner ayithathi indawo yokuhlola i-dermatologic okanye i-biopsy — ezifunekayo ukuze kufumaneke ukuxilongwa okuqinisekileyo — kodwa inika uvavanyo lokuqala oluncedo kunye nokuxhaswa kokulandelela okuqhubekayo.
